Transport mechanisms of tryptophan in blood cells, nerve cells, and at the blood-brain barrier
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Transport mechanisms of tryptophan in blood cells, nerve cells, and at the blood-brain barrier proceedings of the international symposium, Prilly/Lausanne, Switzerland, July 6-7, 1978

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Published by Springer-Verlag in Wien, New York .
Written in English

Subjects:

  • Tryptophan metabolism -- Congresses.,
  • Biological transport -- Congresses.,
  • Blood cells -- Congresses.,
  • Neurons -- Congresses.,
  • Blood-brain barrier -- Congresses.,
  • Tryptophan -- Metabolism -- Congresses.,
  • Blood cells -- Metabolism -- Congresses.,
  • Blood-brain barrier -- Drug effects -- Congresses.,
  • Neurons -- Metabolism -- Congresses.

Book details:

Edition Notes

Includes bibliographies.

Statementedited by P. Baumann.
SeriesJournal of neural transmission : Supplementum ;, 15, Journal of neural transmission., 15.
ContributionsBaumann, P. 1944-
Classifications
LC ClassificationsQP562.T7 T72
The Physical Object
Paginationx, 240 p. :
Number of Pages240
ID Numbers
Open LibraryOL4407289M
ISBN 100387815198
LC Control Number79010471

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Transport Mechanisms of Tryptophan in Blood Cells, Nerve Cells, and at the Blood-Brain Barrier: Proceedings of the International Symposium, (Journal of Neural Transmission. Supplementa) Softcover reprint of the original 1st ed. Edition. Get this from a library! Transport mechanisms of tryptophan in blood cells, nerve cells, and at the blood-brain barrier: proceedings of the international symposium, Prilly/Lausanne, Switzerland, July , [P Baumann;]. Pardridge W.M. () The Role of Blood-Brain Barrier Transport of Tryptophan and Other Neutral Amino Acids in the Regulation of Substrate-Limited Pathways of Brain Amino Acid Metabolism. In: Baumann P. (eds) Transport Mechanisms of Tryptophan in Blood Cells, Nerve Cells, and at the Blood-Brain Barrier. Journal of Neural Transmission, vol Cited by: The role of blood-brain barrier transport of tryptophan and other neutral amino acids in the regulation of substrate-limited pathways of brain amino acid metabolism. Pardridge WM. Many pathways of essential neutral amino acid metabolism in Cited by:

Moreover, it has been proposed that albumin is removed at tryptophan's transport site at the blood brain barrier and plasma l-tryptophan is extracted (Pardridge ;Smith et al. ). The transport of neutral amino acids through the brain capillary endothelial wall, which makes up the blood-brain barrier (BBB) in vivo, is an important control point for the overall regulation of cerebral metabolism, including protein synthesis and neurotransmitter by:   Like you expect, the blood-brain barrier is impermeable to any charged molecule. This is the case of many amino acids circulating in the blood (pH=). Thus amino acids can enter the brain only by using special “revolving door” called solute carriers (SLCs). A cluster of nerve cell bodies outside the central nervous system is referred to as a _____. (see book section: Concept Nervous systems consist of circuits of neurons and supporting cells) cranial nerve brainbow peripheral nerve ganglion None of the listed responses is correct.

The Blood–Brain Barrier. Neurological diseases such as cancers, neurodegenerative diseases, infections, pain, and psychiatric disorders are a leading cause of disability, morbidity, and mortality, affecting more than billion people worldwide, with the number rising if curative treatments fail to emerge (Lalatsa & Barbu, ).Delivery of therapeutics to the brain is Cited by: 5. Composed of: 1. BBB endothelial cells, astrocytes, and neurons. 2. Also composed of pericytes, microglia, vascular smooth muscle and cells circulating in the blood. Laurian S., Grasset F., Steck A., Baumann P., Gaillard JM. () The Influence of Oral Tryptophan on Cortical Evoked Responses in Normals and Schizophrenics. In: Baumann P. (eds) Transport Mechanisms of Tryptophan in Blood Cells, Nerve Cells, and at the Blood-Brain Barrier. Journal of Neural Transmission, vol Springer, ViennaAuthor: S. Laurian, F. Grasset, A. Steck, P. Baumann, J.-M. Gaillard. BBB holds three barrier layers that isolate neural tissues from the blood: (1) highly specialized layer of endothelial cells that partitions blood and interstitial fluid, (2) choroid plexus epithelium that secretes CSF into the ventricles, and (3) arachnoid epithelium which further separates blood from CSF in the subarachnoid spaces (Abbott et Cited by: 2.